Article
TP53 and head and neck neoplasms.
Human mutation - 1 Mar 2003
Blons Hélène, Laurent-Puig Pierre
Abstract excerpt
Head and neck cancer is an important health problem around the world, accounting for approximately 500,000 new cases each year of head and neck squamous cell carcinoma (HNSCC). Carcinogenesis of head and neck results from a dysregulation of cellular proliferation, differentiation, and cell death. The major etiologic agents are tobacco and alcohol consumption and for some cases, human papilloma virus (HPV)...
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