Article
Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer.
Cancer research - 1 Sept 1992
Brachman D G, Graves D, Vokes E, Beckett M, Haraf D, Montag A, Dunphy E, Mick R, Yandell D, Weichselbaum R R
Abstract excerpt
Little is known regarding the molecular genetic events in head and neck carcinoma. Epidemiological evidence suggests that both alcohol and tobacco use are related to the development of these neoplasms, and viral infections have also been postulated to play a role in some tumors. Loss of p53 tumor suppressor gene function has been found in many malignancies and can occur through either gene mutation or by...
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