Article
TP53 mutations in head and neck cancer.
Molecular carcinogenesis - 1 Apr 2022
Nathan Cherie-Ann, Khandelwal Alok R, Wolf Gregory T, Rodrigo Juan P, Mäkitie Antti A, Saba Nabil F, Forastiere Arlene A, Bradford Carol R, Ferlito Alfio
Abstract excerpt
Head and neck squamous cell carcinomas (HNSCCs) arising in the mucosal linings of the upper aerodigestive tract are highly heterogeneous, aggressive, and multifactorial tumors affecting more than half a million patients worldwide each year. Classical etiological factors for HNSCC include alcohol, tobacco, and human papillomavirus (HPV) infection. Current treatment options for HNSCCs encompass surgery,...
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