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Article

Inhibition of Escherichia coli protein synthesis by abortive translation of phage lambda minigenes.

Journal of molecular biology - 6 Jun 1997

Ontiveros C, Valadez J G, Hernández J, Guarneros G

Abstract excerpt

Escherichia coli mutants defective in peptidyl-tRNA hydrolase activity are unable to maintain bacteriophage lambda vegetative growth. Phage mutants, named bar, overcome the host limitation to support viral growth. Multicopy expression of lambda wild-type bar regions is deleterious to hydrolase-defective cells because it provokes arrest of protein synthesis. We noticed that the bar regions include minigenes whose...

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Identifiers

PMID: 9191062
DOI: 10.1006/jmbi.1997.1017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Inhibition of Escherichia coli protein synthesis by abortive translation of phage lambda minigenes.PMID 9191062Read ↗

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Ribosomal RNA and peptidyl-tRNA hydrolase: a peptide chain termination model for lambda bar RNA inhibition.Semantic proximity Read ↗

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Recycling of ribosomal complexes stalled at the step of elongation in Escherichia coli.Semantic proximity Read ↗

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