Article
Increased bar minigene mRNA stability during cell growth inhibition.
Molecular microbiology - 1 Jan 2001
Valadez J G, Hernández-Sánchez J, Magos M A, Ontiveros C, Guarneros G
Abstract excerpt
Bacteriophage lambda is unable to grow vegetatively on Escherichia coli mutants defective in peptidyl-tRNA hydrolase (Pth) activity. Mutations which allow phage growth on the defective host have been located at regions named bar in the lambda genome. Expression of wild-type bar regions from plasmid constructs results in inhibition of protein synthesis and lethality to Pth-defective cells. Two of these wild-type...
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