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Article

Ribosomal RNA and peptidyl-tRNA hydrolase: a peptide chain termination model for lambda bar RNA inhibition.

Biochimie - 1 Dec 1991

Murgola E J, Guarneros G

Abstract excerpt

We propose here a model to explain the inhibition of bacteriophage lambda (lambda) vegetative growth and the killing of E coli cells defective in peptidyl-tRNA hydrolase (Pth) by lambda bar RNA. The model suggests that bar RNA, which contains a characteristic UGA triplet, base-pairs in an anti-pa...

Topics

Bacteriophage lambda
Base Sequence
Carboxylic Ester Hydrolases
Escherichia coli
Models, Genetic
Molecular Sequence Data
Mutation
Peptide Chain Termination, Translational
RNA, Antisense
RNA, Bacterial
RNA, Ribosomal, 16S
RNA, Transfer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Viral

Source

Identifiers

PMID: 1725266
DOI: 10.1016/0300-9084(91)90193-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1725266-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Ribosomal RNA and peptidyl-tRNA hydrolase: a peptide chain termination model for lambda bar RNA inhibition.PMID 1725266Read ↗

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Peptidyl-tRNA hydrolase is involved in lambda inhibition of host protein synthesis.Semantic proximity Read ↗

Increased bar minigene mRNA stability during cell growth inhibition.Semantic proximity Read ↗

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Shutdown in protein synthesis due to the expression of mini-genes in bacteria.Semantic proximity Read ↗

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