Article
HLA class II and susceptibility and resistance to insulin-dependent diabetes mellitus in a population from the northwest of Spain.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1994
Setién Baranda F, Coto E, Menéndez Díaz J, Martínez-Naves E, Alvarez Martínez V, López-Larrea C
Abstract excerpt
The role of HLA class II alleles in genetic predisposition to insulin-dependent diabetes mellitus (IDDM) was examined using Polymerase Chain Reaction/oligonucleotide probe typing (PCR/SSOs) of eight HLA class II loci in 58 IDDM patients and 50 healthy controls from the Northwest of Spain (Asturias). We compared the distribution of HLA class II alleles, haplotypes and genotypes between IDDM patients and controls,...
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