Article
HLA class II and susceptibility and resistance to insulin-dependent diabetes mellitus in a population from the northwest of Spain.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1994
Setién Baranda F, Coto E, Menéndez Díaz J, Martínez-Naves E, Alvarez Martínez V, López-Larrea C
Abstract excerpt
The role of HLA class II alleles in genetic predisposition to insulin-dependent diabetes mellitus (IDDM) was examined using Polymerase Chain Reaction/oligonucleotide probe typing (PCR/SSOs) of eight HLA class II loci in 58 IDDM patients and 50 healthy controls from the Northwest of Spain (Asturia...
Topics
- Adolescent
- Alleles
- Case-Control Studies
- Diabetes Mellitus, Type 1
- Gene Frequency
- Genetic Markers
- Genotype
- HLA-D Antigens
- Haplotypes
- Humans
- Linkage Disequilibrium
- Models, Genetic
- Polymerase Chain Reaction
- Spain