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Article

HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families.

Nature genetics - 1 Apr 1993

Erlich H A, Zeidler A, Chang J, Shaw S, Raffel L J, Klitz W, Beshkov Y, Costin G, Pressman S, Bugawan T

Abstract excerpt

The role of HLA class II alleles in genetic predisposition to insulin dependent diabetes mellitus (IDDM) was examined by PCR/oligonucleotide probe typing of 42 Mexican-American IDDM families derived from Hispanic Caucasians and Native Americans. All high risk haplotypes (HLA-DR3 and DR4) were of European origin while the most strongly protective haplotype (DRB1*1402) was Native American. Of the 16 DR-DQ DR4...

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Source

Identifiers

PMID: 7981758
DOI: 10.1038/ng0493-358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families.PMID 7981758Read ↗

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