The HLA-DRB1*0405 haplotype is most strongly associated with IDDM in Algerians.

doi:10.1111/j.1744-313x.1992.tb00081.x

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Article

The HLA-DRB1*0405 haplotype is most strongly associated with IDDM in Algerians.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Dec 1992

Djoulah S, Khalil I, Beressi J P, Benhamamouch S, Bessaoud K, Deschamps I, Degos L, Hors J

Abstract excerpt

Insulin-dependent diabetes mellitus (IDDM) in Caucasians is strongly associated with HLA-DR3-DQ2 and DR4-DQ8. In order to investigate the HLA class II associations with IDDM in Algerians, we have used polymerase chain reaction (PCR) and sequence specific oligonucleotide analysis (SSO) to identify...

Topics

Algeria
Alleles
Diabetes Mellitus, Type 1
Gene Frequency
Genes, MHC Class II
Genotype
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
Haplotypes
Histocompatibility Antigens Class II
Humans
Polymerase Chain Reaction
White People

Source

Open in PubMed

Identifiers

PMID: 1477090
DOI: 10.1111/j.1744-313x.1992.tb00081.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1477090-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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