Article
The HLA-DRB1*0405 haplotype is most strongly associated with IDDM in Algerians.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Dec 1992
Djoulah S, Khalil I, Beressi J P, Benhamamouch S, Bessaoud K, Deschamps I, Degos L, Hors J
Abstract excerpt
Insulin-dependent diabetes mellitus (IDDM) in Caucasians is strongly associated with HLA-DR3-DQ2 and DR4-DQ8. In order to investigate the HLA class II associations with IDDM in Algerians, we have used polymerase chain reaction (PCR) and sequence specific oligonucleotide analysis (SSO) to identify DQA1, DQB1, and DRB1 alleles, haplotypes and genotypes in 50 unrelated IDDM patients and 46 controls from a...
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