Article
HLA-DQA1 and DQB1 allele and genotype contribution to IDDM susceptibility in an ethnically mixed population.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Dec 1994
Balducci-Silano P L, Layrisse Z, Dominguez E, Amaro R, Gunczler P, Lanes R, Zaro R
Abstract excerpt
HLA-DRB1, DQA1 and DQB1 alleles have been determined in 42 families with one IDDM proband and 64 healthy controls, by oligotyping (PCR-SSO) using primers and probes from the XI International Histocompatibility Workshop. A positive DRB1*03 and DRB1*04 association with the disease was observed, whereas DRB1*11 and DRB1*07 showed negative association but 19% of patients carried DRB1 alleles different to DRB1*03 or...
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