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Article

HLA-DQB1 alleles and absence of Asp 57 as susceptibility factors of IDDM in Finland.

Diabetes - 1 Dec 1991

Reijonen H, Ilonen J, Knip M, Akerblom H K

Abstract excerpt

It has been proposed that negatively charged aspartic acid at position 57 of the HLA-DQ beta-chain determines resistance to development of insulin-dependent diabetes mellitus (IDDM), whereas genetic susceptibility to IDDM correlates with a neutral amino acid residue. The disease rate is very low in Oriental populations with high frequencies of Asp 57. This raises a question whether the high incidence of IDDM in...

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Identifiers

PMID: 1756904
DOI: 10.2337/diab.40.12.1640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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