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Article

HLA class II-associated predisposition to insulin-dependent diabetes mellitus in a Polish population.

Human immunology - 1 Jul 1998

Krokowski M, Bodalski J, Bratek A, Boitard C, Caillat-Zucman S

Abstract excerpt

Susceptibility and resistance to insulin-dependent diabetes mellitus (IDDM) are strongly associated with alleles of HLA class II DR and DQ genes. We have studied HLA DRB1, DQA1, DQB1 allele and haplotype distribution in 152 IDDM children and 103 unrelated healthy individuals from the region of Lodz in central Poland by the polymerase chain reaction and hybridisation with allele-specific oligonucleotide probes....

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Source

Identifiers

PMID: 9684995
DOI: 10.1016/s0198-8859(98)00036-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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HLA class II-associated predisposition to insulin-dependent diabetes mellitus in a Polish population.PMID 9684995Read ↗

HLA class II allele and haplotype distribution in a population from central Poland.Semantic proximity Read ↗

[DQA1 and DQB1 HLA genes as markers of insulin-dependent diabetes mellitus in the Polish population].Semantic proximity Read ↗

DRB1*0403 protects against IDDM in Caucasians with the high-risk heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 genotype. Belgian Diabetes Registry.Semantic proximity Read ↗

HLA-DRB1*0401 is associated with susceptibility to insulin-dependent diabetes mellitus independently of the DQB1 locus.Semantic proximity Read ↗

HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibria in a Chinese population.Semantic proximity Read ↗

HLA class II polymorphism and IDDM susceptibility in the Greek population.Semantic proximity Read ↗

HLA-DR and -DQ associations with insulin-dependent diabetes mellitus in a population of Turkey.Semantic proximity Read ↗

The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families.Semantic proximity Read ↗

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Heterogeneity of HLA genetic factors in IDDM susceptibility.Semantic proximity Read ↗

HLA-DRB1*0403 is associated with dominant protection against IDDM in the general Dutch population and subjects with high-risk DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 genotype.Semantic proximity Read ↗

Different contribution of HLA-DR and -DQ genes in susceptibility and resistance to insulin-dependent diabetes mellitus (IDDM).Semantic proximity Read ↗

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