Article
HLA-DR and -DQ associations with insulin-dependent diabetes mellitus in a population of Turkey.
Human immunology - 1 Mar 2000
Saruhan-Direskeneli G, Uyar F A, Bas F, Günöz H, Bundak R, Saka N, Darendeliler F
Abstract excerpt
Genetic susceptibility to insulin-dependent diabetes mellitus (IDDM) has been shown to be associated with MHC in many studies. To extend this data with a population with relatively low IDDM incidence, MHC DRB, DQA, and DQB have been investigated by polymerase chain reaction and sequence specific oligonucleotide probe hybridization (PCR/SSO) in 178 IDDM patients from Turkey and compared to 248 healthy controls....
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