Article
Allele doses of apolipoprotein E type epsilon 4 in sporadic late-onset Alzheimer's disease.
American journal of medical genetics - 18 Dec 1995
Lucotte G, Aouizérate A, Gérard N, Turpin J C, Landais P
Abstract excerpt
Apoliprotein E, type epsilon 4 allele (ApoE-epsilon 4) is associated with late-onset sporadic Alzheimer's disease (AD). We have found that the cumulative probability of remaining unaffected over time decreases for each dose of ApoE-epsilon 4 in sporadic, late-onset French AD. The effect of genotypes on age at onset of AD was analyzed using the product limit method, to compare unaffected groups during aging.
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