Dose-dependent association of apolipoprotein E allele epsilon 4 with late-onset, sporadic Alzheimer's disease.

doi:10.1002/ana.410360416

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Article

Dose-dependent association of apolipoprotein E allele epsilon 4 with late-onset, sporadic Alzheimer's disease.

Annals of neurology - 1 Oct 1994

Yoshizawa T, Yamakawa-Kobayashi K, Komatsuzaki Y, Arinami T, Oguni E, Mizusawa H, Shoji S, Hamaguchi H

Abstract excerpt

We examined the apolipoprotein E (apo E) genotypes in 47 patients with late-onset sporadic Alzheimer's disease (mean age at onset +/- standard deviation, 72.2 +/- 6.4 years), 8 with late-onset familial Alzheimer's disease (75.5 +/- 5.1 years), 18 with early-onset sporadic Alzheimer's disease (52....

Topics

Aged
Alleles
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Asian People
Female
Gene Dosage
Gene Frequency
Humans
Japan
Male
Middle Aged

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