Article
Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.
Lancet (London, England) - 18 Sept 1993
Saunders A M, Schmader K, Breitner J C, Benson M D, Brown W T, Goldfarb L, Goldgaber D, Manwaring M G, Szymanski M H, McCown N
Abstract excerpt
The frequency of the allele for apolipoprotein E type 4 (epsilon 4) is increased in late-onset familial and sporadic Alzheimer's disease (AD). We have examined epsilon 4 frequencies in four distinct, normal, elderly control groups and, most importantly, in patients with amyloid-forming diseases whose epsilon 4 distributions were not previously known (Creutzfeldt-Jakob disease, familial amyloidotic polyneuropathy,...
Read the complete abstract on PubMedTopics
- Age Factors
- Aged
- Alleles
- Alzheimer Disease
- Amyloidosis
- Apolipoprotein E4