Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of APOE with age at onset of sporadic amyotrophic lateral sclerosis.

Journal of the neurological sciences - 15 Oct 2008

Zetterberg Henrik, Jacobsson Johan, Rosengren Lars, Blennow Kaj, Andersen Peter M

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative syndrome with familial and sporadic forms. We conducted a study including 60 sporadic and 19 familial ALS patients, 206 reference patients with other neurological disorders and 1265 neurologically healthy controls to assess the Alzheimer-associated apolipoprotein E (APOE) epsilon4 gene variant as a possible risk factor for ALS. While no major influence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged, 80 and over
Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Gene Frequency

Share to Superoxide Dismutase

Share to Superoxide Dismutase-1

Share to Survival Analysis

Source

Identifiers

PMID: 18656208
DOI: 10.1016/j.jns.2008.06.025

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of APOE with age at onset of sporadic amyotrophic lateral sclerosis.PMID 18656208Read ↗

Apolipoprotein E is associated with age at onset of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Apolipoprotein E epsilon 4 allele is not associated with earlier age at onset in amyotrophic lateral sclerosis.Semantic proximity Read ↗

APOE ε4 allele is associated with an increased risk of bulbar-onset amyotrophic lateral sclerosis in men.Semantic proximity Read ↗

Lack of association between APOE gene polymorphisms and amyotrophic lateral sclerosis: a comprehensive meta-analysis.Semantic proximity Read ↗

Apolipoprotein E genotyping in sporadic amyotrophic lateral sclerosis: evidence for a major influence on the clinical presentation and prognosis.Semantic proximity Read ↗

Association of apolipoprotein E ε4 allele and amyotrophic lateral sclerosis in Chinese population.Semantic proximity Read ↗

APOE ε4 Allele is Associated with Cognitive Impairment in Chinese Sporadic ALS: A Retrospective Cohort Study.Semantic proximity Read ↗

APOE: a potential marker of disease progression in ALS.Semantic proximity Read ↗

Association of APOE epsilon4 allele with survival in amyotrophic lateral sclerosis.Semantic proximity Read ↗

APOE epsilon 4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway.Semantic proximity Read ↗

Association of apolipoprotein E allele epsilon 4 with late-onset sporadic Alzheimer's disease.Semantic proximity Read ↗

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.