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Article

Apolipoprotein E polymorphism is associated with both senile plaque load and Alzheimer-type neurofibrillary tangle formation.

Annals of the New York Academy of Sciences - 17 Jan 1996

März W, Scharnagl H, Kirça M, Bohl J, Gross W, Ohm T G

Abstract excerpt

Recent work provided evidence that the apolipoprotein (apo) E polymorphism is associated with late-onset sporadic Alzheimer's disease. The major histological hallmarks of Alzheimer's disease are the extraneuronal deposition of A4/beta-amyloid and the intraneuronal formation of neurofibrillary tan...

Topics

Aging
Alleles
Alzheimer Disease
Apolipoproteins E
Brain
Genotype
Humans
Middle Aged
Neurofibrillary Tangles
Polymorphism, Genetic
Regression Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8624098
DOI: 10.1111/j.1749-6632.1996.tb34432.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8624098-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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