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Article

Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease.

Neurology - 1 Jul 1995

Corder E H, Saunders A M, Strittmatter W J, Schmechel D E, Gaskell P C, Rimmler J B, Locke P A, Conneally P M, Schmader K E, Tanzi R E

Abstract excerpt

The apolipoprotein E (APOE) epsilon 4 allele carries an increased risk of a patient developing Alzheimer's disease (AD) while the epsilon 2 allele carries a decreased risk. We compared survival from the onset of AD in subjects with different numbers of epsilon 4 alleles and evaluated changes in genotypic frequencies with age. Two subject groups were investigated: unrelated AD case and control subjects, and...

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Source

Identifiers

PMID: 7617191
DOI: 10.1212/wnl.45.7.1323

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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