Article
Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease.
Neurology - 1 Jul 1995
Corder E H, Saunders A M, Strittmatter W J, Schmechel D E, Gaskell P C, Rimmler J B, Locke P A, Conneally P M, Schmader K E, Tanzi R E
Abstract excerpt
The apolipoprotein E (APOE) epsilon 4 allele carries an increased risk of a patient developing Alzheimer's disease (AD) while the epsilon 2 allele carries a decreased risk. We compared survival from the onset of AD in subjects with different numbers of epsilon 4 alleles and evaluated changes in g...
Topics
- Age of Onset
- Aged
- Alleles
- Alzheimer Disease
- Apolipoprotein E3
- Apolipoprotein E4
- Apolipoproteins E
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Risk Factors