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Article

Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system.

Proceedings of the National Academy of Sciences of the United States of America - 17 Sept 1996

Vidal M, Braun P, Chen E, Boeke J D, Harlow E

Abstract excerpt

Many biological processes rely upon protein-protein interactions. Hence, detailed analysis of these interactions is critical for their understanding. Due to the complexities involved, genetic approaches are often needed. In yeast and phage, genetic characterizations of protein complexes are possible. However, in multicellular organisms, such characterizations are limited by the lack of powerful selection systems....

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Identifiers

PMID: 8816798
DOI: 10.1073/pnas.93.19.10321
PMCID: PMC38382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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