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Article

Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions.

Proceedings of the National Academy of Sciences of the United States of America - 17 Sept 1996

Vidal M, Brachmann R K, Fattaey A, Harlow E, Boeke J D

Abstract excerpt

Macromolecular interactions define many biological phenomena. Although genetic methods are available to identify novel protein-protein and DNA-protein interactions, no genetic system has thus far been described to identify molecules or mutations that dissociate known interactions. Herein, we desc...

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Identifiers

PMID: 8816797
DOI: 10.1073/pnas.93.19.10315
PMCID: PMC38381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8816797-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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