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Article

Critical role of Ras in the proliferation and prevention of apoptosis mediated by IL-2.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 1996

Gómez J, Martínez-A C, Fernández B, García A, Rebollo A

Abstract excerpt

Activation of the Ras small guanine nucleotide-binding proteins upon IL-2 stimulation of T lymphocytes has been described previously. However, the relevance of the Ras molecules in the cellular events triggered by IL-2 still remained to be clarified. To analyze the effects of Ras inhibition in early proliferative responses to IL-2, we have transiently expressed a Ras dominant negative mutant carrying a point...

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PMID: 8805624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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