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Article

Implication of the small GTPase Rac1 in the apoptosis induced by UV in Rat-2 fibroblasts.

Biochemical and biophysical research communications - 20 Jul 2001

Eom Y W, Yoo M H, Woo C H, Hwang K C, Song W K, Yoo Y J, Chun J S, Kim J H

Abstract excerpt

Exposure of mammalian cells to ultraviolet (UV) light elicits a cellular response and also lead to apoptotic cell death. However, the role of Rac, a member of Rho family GTPases, in the UV-induced apoptosis has never been examined. In UV-irradiated Rat-2 fibroblasts, nuclear fragmentation began to be observed within 2 h and the total viability of Rat-2 cells were only about 15% at 6 h following by UV irradiation,...

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Identifiers

PMID: 11453667
DOI: 10.1006/bbrc.2001.5233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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