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Article

An uncertain role for p53 gene alterations in human prostate cancers.

Cancer research - 15 Aug 1996

Brooks J D, Bova G S, Ewing C M, Piantadosi S, Carter B S, Robinson J C, Epstein J I, Isaacs W B

Abstract excerpt

Inactivation of the p53 gene has been implicated in prostate cancer progression. To determine the role of p53 inactivation in the progression of clinical prostatic carcinomas, we assessed 67 tumors derived from patients with clinically localized disease for chromosome 17p and p53 gene allelic loss, p53 gene mutations using single-strand conformational polymorphism and direct sequencing, and p53 protein expression...

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PMID: 8706029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An uncertain role for p53 gene alterations in human prostate cancers.PMID 8706029Read ↗

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