An uncertain role for p53 gene alterations in human prostate cancers.

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Article

An uncertain role for p53 gene alterations in human prostate cancers.

Cancer research - 15 Aug 1996

Brooks J D, Bova G S, Ewing C M, Piantadosi S, Carter B S, Robinson J C, Epstein J I, Isaacs W B

Abstract excerpt

Inactivation of the p53 gene has been implicated in prostate cancer progression. To determine the role of p53 inactivation in the progression of clinical prostatic carcinomas, we assessed 67 tumors derived from patients with clinically localized disease for chromosome 17p and p53 gene allelic los...

Topics

Base Sequence
Chromosome Deletion
Chromosomes, Human, Pair 17
Genes, p53
Humans
Immunohistochemistry
Male
Molecular Sequence Data
Mutation
Neoplasm Metastasis
Polymorphism, Single-Stranded Conformational
Prostatic Neoplasms
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 8706029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8706029-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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