Article
Tumor suppressor gene p53 mutations in human prostate cancer.
The Prostate - 1 Jul 1995
Kubota Y, Shuin T, Uemura H, Fujinami K, Miyamoto H, Torigoe S, Dobashi Y, Kitamura H, Iwasaki Y, Danenberg K
Abstract excerpt
The genetic background underlying the growth and development of human prostatic cancer is not yet clear. Here we searched for possible mutations in the entire coding region of tumor suppressor gene p53 in primary human prostatic carcinomas, using polymerase chain reaction and single-strand confor...
Topics
- Adenocarcinoma
- Base Sequence
- DNA, Neoplasm
- Exons
- Genes, p53
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Prostatic Neoplasms