Article
p53 oncogene mutations in human prostate cancer specimens.
The Journal of urology - 1 Feb 1994
Voeller H J, Sugars L Y, Pretlow T, Gelmann E P
Abstract excerpt
Eighty-five prostate cancer specimens from prostate resections were analyzed for the presence of p53 gene mutations by immunohistochemical staining for P53 protein. DNA from thirty-four of these samples was also analyzed for mutations in exons 5-8 by single-strand chain polymorphism (SSCP) analysis. One sample had P53 staining by immunohistochemistry, one sample was positive for a p53 mutation by SSCP, and one...
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