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Article

Loss of heterozygosity and overexpression of p53 gene in human primary prostatic adenocarcinoma.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 1994

Fan K, Dao D D, Schutz M, Fink L M

Abstract excerpt

We have examined the loss of heterozygosity (LOH) of codon 72 and evaluated the overexpression of the tumor suppressor gene p53 in 43 primary human prostatic adenocarcinomas (PC). DNA from tumors and normal tissues were extracted from radical prostatectomy specimens. LOH was determined by restriction fragment length polymorphism analysis (RFLP) of the codon-specific endonuclease-digested polymerase chain reaction...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7866637
DOI: 10.1097/00019606-199412000-00009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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