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Article

Clinical significance of p53 alterations in surgically treated prostate cancers.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2008

Schlomm Thorsten, Iwers Liv, Kirstein Patrick, Jessen Birte, Köllermann Jens, Minner Sarah, Passow-Drolet Annika, Mirlacher Martina, Milde-Langosch Karin, Graefen Markus, Haese Alexander, Steuber Thomas, Simon Ronald, Huland Hartwig, Sauter Guido, Erbersdobler Andreas

Abstract excerpt

Despite the high number of previous studies, the role of p53 alterations in prostate cancer is not clearly defined. To address the role of p53 alterations in prostate cancer biology, a total of 2514 cancers treated by radical prostatectomy were successfully analyzed by immunohistochemistry in a tissue microarray format. Overall a low rate of p53-positive tumors was found (2.5%). A significant underestimation of...

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PMID: 18552821
DOI: 10.1038/modpathol.2008.104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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