Molecular genetic alterations of chromosome 17 and p53 nuclear overexpression in human bladder cancer.

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Article

Molecular genetic alterations of chromosome 17 and p53 nuclear overexpression in human bladder cancer.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Mar 1993

Dalbagni G, Presti J C, Reuter V E, Zhang Z F, Sarkis A S, Fair W R, Cordon-Cardo C

Abstract excerpt

We set out to define the alterations of chromosome 17 in human bladder tumors and to correlate p53 nuclear over-expression with 17p deletions in those neoplasms. We studied 60 bladder tumors by restriction fragment-length polymorphism analysis directed at five different loci on chromosome 17. The...

Topics

Alleles
Chromosomes, Human, Pair 17
Genes, p53
Humans
Immunoenzyme Techniques
Incidence
Mutation
Polymorphism, Restriction Fragment Length
Tumor Suppressor Protein p53
Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 7904525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7904525-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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