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Article

Molecular genetic alterations of chromosome 17 and p53 nuclear overexpression in human bladder cancer.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Mar 1993

Dalbagni G, Presti J C, Reuter V E, Zhang Z F, Sarkis A S, Fair W R, Cordon-Cardo C

Abstract excerpt

We set out to define the alterations of chromosome 17 in human bladder tumors and to correlate p53 nuclear over-expression with 17p deletions in those neoplasms. We studied 60 bladder tumors by restriction fragment-length polymorphism analysis directed at five different loci on chromosome 17. The same tumors were studied with a panel of mouse monoclonal antibodies (PAb1801, PAb240, and PAb1620) to mutant and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 7904525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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