Tumor suppressor genes in prostatic oncogenesis.

Article

Tumor suppressor genes in prostatic oncogenesis.

Journal of cellular biochemistry. Supplement - 1 Jan 1994

Bookstein R

Abstract excerpt

Mutations of tumor suppressor genes are critical genetic alterations occurring during the genesis and progression of human cancer, and consequently are candidates for use as surrogate endpoint biomarkers. The two most intensively studied suppressor genes, retinoblastoma (Rb) and p53, are mutated...

Topics

Biomarkers, Tumor
DNA, Neoplasm
Exons
Gene Expression
Genes, Retinoblastoma
Genes, Tumor Suppressor
Genes, p53
Humans
Male
Mutation
Point Mutation
Prostatic Neoplasms
Tumor Suppressor Protein p53

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