Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 gene alterations in human prostate carcinoma.

The Journal of urology - 1 Jul 1993

Effert P J, McCoy R H, Walther P J, Liu E T

Abstract excerpt

Alterations of the p53 gene are among the most frequent genetic lesions in a variety of human malignancies. Their role in prostate cancer is, however, unclear. We have analyzed 10 primary and two metastatic human prostate carcinomas as well as 3 prostate cancer cell lines for mutations of the p53-gene. Using single strand conformational polymorphism analysis (SSCP) and direct sequencing of the polymerase chain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Neoplasm
Share to Electrophoresis, Polyacrylamide Gel
Share to Genes, p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Prostatic Neoplasms

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 8510267
DOI: 10.1016/s0022-5347(17)35458-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 gene alterations in human prostate carcinoma.PMID 8510267Read ↗

Tumor suppressor gene p53 mutations in human prostate cancer.Semantic proximity Read ↗

p53 oncogene mutations in human prostate cancer specimens.Semantic proximity Read ↗

p53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in the primary site define foci with metastatic potential.Semantic proximity Read ↗

Alterations of the P53 gene are associated with the progression of a human prostate carcinoma.Semantic proximity Read ↗

P53 tumour-suppressor gene mutations are mainly localised on exon 7 in human primary and metastatic prostate cancer.Semantic proximity Read ↗

An uncertain role for p53 gene alterations in human prostate cancers.Semantic proximity Read ↗

Frequency and characterization of p53 mutations in primary and metastatic human prostate cancer.Semantic proximity Read ↗

Alterations of p53 are common in early stage prostate cancer.Semantic proximity Read ↗

p53 abnormalities in primary prostate cancer: single-strand conformation polymorphism analysis of complementary DNA in comparison with genomic DNA. The Cooperative Prostate Network.Semantic proximity Read ↗

p53 mutations occur in clinical, but not latent, human prostate carcinoma.Semantic proximity Read ↗

Alteration of the p53 locus in benign hyperplastic prostatic epithelium associated with high-grade prostatic adenocarcinoma.Semantic proximity Read ↗

Identification of p53 mutations in archival prostate tumors. Sensitivity of an optimized single-strand conformational polymorphism (SSCP) assay.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.