Article
Modeling the number and size of hepatic focal lesions following exposure to 2,3,7,8-TCDD.
Toxicology and applied pharmacology - 1 May 1996
Portier C J, Sherman C D, Kohn M, Edler L, Kopp-Schneider A, Maronpot R M, Lucier G
Abstract excerpt
Data on the size and number of placental glutathione S-transferase-positive (PGST+) foci were collected from a two-stage hepatocarcinogenesis model in female Sprague-Dawley rats. the study consisted of multiple 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-exposed dose groups including both diethyln...
Topics
- Adenosine Triphosphate
- Animals
- Carcinogens
- Diethylnitrosamine
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Female
- Glucose-6-Phosphatase
- Glutathione Transferase
- Liver
- Liver Neoplasms, Experimental