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Article

Role of cell proliferation at early stages of hepatocarcinogenesis.

Toxicology letters - 1 Dec 1995

Schwarz M, Buchmann A, Bock K W

Abstract excerpt

Hepatocarcinogenesis in rodents is characterized by the early appearance of foci of enzyme-altered (initiated) cells which are believed to represent precursors on the way to malignancy. Proliferation of cells within enzyme-altered liver foci is generally increased as compared to surrounding normal hepatocytes. This may be mediated by changes in the rates of cell division and/or cell death (apoptosis). Cell...

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PMID: 8597064
DOI: 10.1016/0378-4274(95)03465-x

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