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Article

Quantitation of Multistage Carcinogenesis in Rat Liver

1 Jan 1996

Abstract excerpt

A well characterized model of multistage carcinogenesis is that of hepatocarcinogenesis in the rat. The histopathology as well as the cell and molecular biology of the stages of initiation, promotion, and progression have been elucidated to varying degrees in this system. Putatively single initiated hepatocytes are identified by their expression of the ubiquitous marker of hepatocarcinogenesis,...

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PMID: 8839289
DOI: 10.1177/019262339602400116

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