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Article

Analysis of rat liver foci growth with a quantitative two-cell model after treatment with 2,4,5,3',4'-pentachlorobiphenyl.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Sept 2000

Haag-Grönlund M, Conolly R, Scheu G, Wärngård L, Fransson-Steen R

Abstract excerpt

A biologically based, quantitative foci-growth model was used to analyze the effect of 20 and 52 weeks treatment with 2,4,5,3', 4'-pentachlorobiphenyl (PCB118) on the development of enzyme-altered foci in rat liver initiated with partial hepatectomy and diethylnitrosamine. Hepatocyte proliferation was examined and the data were used in the selection of division rates for the computer simulations of foci growth....

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Identifiers

PMID: 10966509
DOI: 10.1093/toxsci/57.1.32

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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