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Article

Conclusion of LOD-score analysis for family data generated under two-locus models.

American journal of human genetics - 1 Jun 1996

Dizier M H, Babron M C, Clerget-Darpoux F

Abstract excerpt

The power to detect linkage by the LOD-score method is investigated here for diseases that depend on the effects of two genes. The classical strategy is, first, to detect a major-gene (MG) effect by segregation analysis and, second, to seek for linkage with genetic markers by the LOD-score method using the MG parameters. We already showed that segregation analysis can lead to evidence for a MG effect for many...

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Identifiers

PMID: 8651311
PMCID: PMC1915060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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