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Article

Conclusions of segregation analysis for family data generated under two-locus models.

American journal of human genetics - 1 Dec 1993

Dizier M H, Bonaïti-Pellié C, Clerget-Darpoux F

Abstract excerpt

Susceptibility to a disease may involve the interactive effect of two genes. What conclusions will be drawn by segregation analysis in such a case? To answer this question, we considered a set of two-locus models and the corresponding exact distribution for 300 families. We investigated the conclusions and parameter estimations obtained for this sample, by comparing the likelihood expectations of the unified...

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Identifiers

PMID: 8250049
PMCID: PMC1682497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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