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Article

Effect of heterogeneity and assumed mode of inheritance on lod scores.

American journal of medical genetics - 1 Feb 1992

Durner M, Greenberg D A

Abstract excerpt

Heterogeneity is a major factor in many common, complex diseases and can confound linkage analysis. Using computer-simulated heterogeneous data we tested what effect unlinked families have on a linkage analysis when heterogeneity is not taken into account. We created 60 data sets of 40 nuclear families each with different proportions of linked and unlinked families and with different modes of inheritance. The...

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Identifiers

PMID: 1536160
DOI: 10.1002/ajmg.1320420302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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