Article
Impact of sample selection on APOE epsilon 4 allele frequency: a comparison of two Alzheimer's disease samples.
Journal of the American Geriatrics Society - 1 Jun 1996
Tsuang D, Kukull W, Sheppard L, Barnhart R L, Peskind E, Edland S D, Schellenberg G, Raskind M, Larson E B
Abstract excerpt
OBJECTIVE: In a highly selected sample of unrelated Alzheimer's disease (AD) patients, we found that the APOE epsilon 4 allele frequency was higher than previously reported. Differing selection and ascertainment criteria may lead to these differences. To address this possibility, we compared the epsilon 4 allele frequency in two samples of AD patients selected from the same geographical area. SETTING AND...
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