Article
Apolipoprotein E-epsilon 4 allele and familial risk in Alzheimer's disease.
Genetic epidemiology - 1 Jan 1996
Li G, Silverman J M, Altstiel L D, Haroutunian V, Perl D P, Purohit D, Birstein S, Lantz M, Mohs R C, Davis K L
Abstract excerpt
Recent studies have found an association between presence of apolipoprotein E (APOE) epsilon 4 allele and Alzheimer's disease (AD). The present study compared the cumulative risk of primary progressive dementia (PPD) in relatives of AD probands carrying at least one copy of the epsilon 4 allele with the relatives of AD probands not carrying epsilon 4 and with relatives of non-demented controls. Our aim was to...
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