Article
Apolipoprotein E-epsilon 4 allele and familial risk in Alzheimer's disease.
Genetic epidemiology - 1 Jan 1996
Li G, Silverman J M, Altstiel L D, Haroutunian V, Perl D P, Purohit D, Birstein S, Lantz M, Mohs R C, Davis K L
Abstract excerpt
Recent studies have found an association between presence of apolipoprotein E (APOE) epsilon 4 allele and Alzheimer's disease (AD). The present study compared the cumulative risk of primary progressive dementia (PPD) in relatives of AD probands carrying at least one copy of the epsilon 4 allele w...
Topics
- Age of Onset
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Analysis of Variance
- Apolipoprotein E4
- Apolipoproteins E
- Case-Control Studies
- Cause of Death
- Coronary Disease
- Dementia
- Demography
- Female
- Genotype
- Humans
- Male
- Middle Aged