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Article

The apolipoprotein E epsilon4 allele is not a significant risk factor for frontotemporal dementia.

Annals of neurology - 1 Jul 1998

Geschwind D, Karrim J, Nelson S F, Miller B

Abstract excerpt

Frontotemporal dementia (FTD) is the most common early-onset non-Alzheimer's dementia (non-AD). Although the role of the epsilon4 allele of apolipoprotein E (ApoE) has been well established in AD, studies of ApoE allele distribution in patients with FTD have produced variable results. We studied 33 rigorously diagnosed FTD patients, including several who were pathologically confirmed, and compared the frequency...

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PMID: 9667603
DOI: 10.1002/ana.410440122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The apolipoprotein E epsilon4 allele is not a significant risk factor for frontotemporal dementia.PMID 9667603Read ↗

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