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Article

ApoE epsilon 4 allelic association with Alzheimer's disease: independent confirmation using denaturing gradient gel electrophoresis.

Neurology - 1 Feb 1994

Peacock M L, Fink J K

Abstract excerpt

There is intriguing evidence associating apolipoprotein E (ApoE) with Alzheimer's disease (AD). ApoE is deposited with beta-amyloid in senile plaques and binds to beta-amyloid in vitro. We used denaturing gradient gel electrophoresis to identify ApoE epsilon 2, epsilon 3, and epsilon 4 alleles in...

Topics

Aged
Alleles
Alzheimer Disease
Apolipoproteins E
Cerebellum
DNA
Electrophoresis, Polyacrylamide Gel
Exons
Genotype
Humans
Leukocytes
Middle Aged
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8309587
DOI: 10.1212/wnl.44.2.339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8309587-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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