Rescue of the tail defect of Brachyury mice.

doi:10.1101/gad.7.2.197

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Article

Rescue of the tail defect of Brachyury mice.

Genes & development - 1 Feb 1993

Stott D, Kispert A, Herrmann B G

Abstract excerpt

The mouse Brachyury (T) gene is required for normal development of axial structures. Embryos homozygous for the T mutation show severe deficiencies in mesoderm formation. They lack the notochord and allantois, have abnormal somites, and die at approximately 10 days postcoitum probably as a result...

Topics

Allantois
Animals
Base Sequence
Cloning, Molecular
Dosage Compensation, Genetic
Mice
Mice, Transgenic
Molecular Sequence Data
Mutation
Notochord
Phenotype
Tail

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