Article
Expression of T protein in the primitive streak is necessary and sufficient for posterior mesoderm movement and somite differentiation.
Developmental biology - 1 Dec 1997
Wilson V, Beddington R
Abstract excerpt
A characteristic abnormality of chimeras composed of wildtype and T/T (Brachyury) mutant embryonic stem cells is the aggregation and accumulation of mutant cells in the primitive streak and its descendant, the tail bud (V. Wilson, L. Manson, W. C. Skarnes, and R. S. P. Beddington (1995). Developm...
Topics
- Animals
- Cell Differentiation
- Cell Movement
- Chimera
- Clone Cells
- DNA-Binding Proteins
- Female
- Fetal Proteins
- Gene Expression Regulation, Developmental
- Homozygote
- In Situ Hybridization
- Male
- Mesoderm
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Mutation
- Pregnancy