Article
Brachyury--a gene affecting mouse gastrulation and early organogenesis.
Development (Cambridge, England). Supplement - 1 Jan 1992
Beddington R S, Rashbass P, Wilson V
Abstract excerpt
Mouse embryos that are homozygous for the Brachyury (T) deletion die at mid-gestation. They have prominent defects in the notochord, the allantois and the primitive streak. Expression of the T gene commences at the onset of gastrulation and is restricted to the primitive streak, mesoderm emerging from the streak, the head process and the notochord. Genetic evidence has suggested that there may be an increasing...
Topics
- Animals
- Chimera
- Gastrula
- Genes
- Mice
- Mice, Mutant Strains
- Morphogenesis
- Phenotype
- Stem Cells