Article
Cloning of the T gene required in mesoderm formation in the mouse.
Nature - 15 Feb 1990
Herrmann B G, Labeit S, Poustka A, King T R, Lehrach H
Abstract excerpt
The murine developmental mutation T identifies an essential gene in mesoderm formation. Embryos lacking normal gene activity fail to form the notochord, the entire posterior region and the allantois, and die at about 10 days of gestation. We have isolated the T gene using a combination of molecul...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Deletion
- Chromosome Mapping
- Cloning, Molecular
- DNA Transposable Elements
- Embryo, Mammalian
- Genes
- Mesoderm
- Mice
- Molecular Sequence Data
- Restriction Mapping