Article
Identification of a novel mouse brachyury (T) allele causing a short tail mutation in mice.
Cell biochemistry and biophysics - 1 Dec 2010
Wu Baojin, Shao Yixiang, Chen Bing, Liu Chun, Xue Zhengfeng, Wu Peilin, Li Houda
Abstract excerpt
Mutations in T-box genes are associated with numerous disease states in humans. The objective of this paper was to characterize the T(shao), a specific T-box mutation, in mice. T(shao), a short-tailed mutant mouse strain in a B6 background, was obtained by ethylnitrosourea mutagenesis. Microsatellite genomic scans mapped the location of the mutation. RT-PCR was used to amplify the identified region and the...
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