Article
Does the T gene determine the anteroposterior axis of a mouse embryo?
Idengaku zasshi - 1 Oct 1990
Yanagisawa K O
Abstract excerpt
The t complex in the mouse is essential to embryonic development. The semidominant mutation, T, is embryonic lethal in homozygotes. In T/T embryos, proper morphogenetic movement is hindered, causing the number of mesodermal cells to be reduced. The other effect of T mutation is shortening of the tail in heterozygotes, T/+ and T/t. t is a series of recessive mutations in the t complex. A detailed examination of...
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