The T-box gene family.

doi:10.1002/(SICI)1521-1878(199801)20:1<9::AID-BIES4>3.0.CO;2-Q

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Article

The T-box gene family.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jan 1998

Papaioannou V E, Silver L M

Abstract excerpt

A novel family of transcription factors that appears to play a critical role in the development of all animal species was recently uncovered on the basis of homology of the DNA binding domain of the Brachyury, or T locus, gene product. Phylogenetic studies have shown the ancient origin of this ge...

Topics

Animals
DNA-Binding Proteins
Embryonic and Fetal Development
Fetal Proteins
Gene Expression Regulation, Developmental
Humans
Mice
Multigene Family
Mutation
Phylogeny
T-Box Domain Proteins
Transcription Factors
Brachyury Protein

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