Article
Effects of the TWis mutation on notochord formation and mesodermal patterning.
Mechanisms of development - 1 Feb 1995
Conlon F L, Wright C V, Robertson E J
Abstract excerpt
The mouse T (Brachyury) gene is required for early mesodermal patterning. Mice homozygous for mutations in T die at midgestation and display defects in mesodermal tissues such as the notochord, the allantois and the somitic mesoderm. To examine the role of T in patterning of somitic and posterior...
Topics
- Alleles
- Animals
- Biomarkers
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Fetal Proteins
- Mesoderm
- Mice
- Mice, Mutant Strains
- Mutation
- Notochord
- T-Box Domain Proteins
- Brachyury Protein