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Article

Effects of the TWis mutation on notochord formation and mesodermal patterning.

Mechanisms of development - 1 Feb 1995

Conlon F L, Wright C V, Robertson E J

Abstract excerpt

The mouse T (Brachyury) gene is required for early mesodermal patterning. Mice homozygous for mutations in T die at midgestation and display defects in mesodermal tissues such as the notochord, the allantois and the somitic mesoderm. To examine the role of T in patterning of somitic and posterior mesoderm along the anterior-posterior axis, we have examined the expression of a panel of molecular markers normally...

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Identifiers

PMID: 7734393
DOI: 10.1016/0925-4773(94)00318-h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of the TWis mutation on notochord formation and mesodermal patterning.PMID 7734393Read ↗

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Expression of T protein in the primitive streak is necessary and sufficient for posterior mesoderm movement and somite differentiation.Semantic proximity Read ↗

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